When drug nanocarriers miss their target: extracellular diffusion and cell uptake are not enough to be effective
Author:
Affiliation:
1. Institut Galien Paris-Saclay
2. UMR 8612
3. CNRS
4. Université Paris-Saclay
5. Faculté de Pharmacie
6. Institut des matériaux poreux de Paris
7. Ecole normale supérieure
8. ESPCI Paris
9. PSL University
Abstract
Screening on a relevant 3D tumor model enabled to discard unpromising nanocarriers and may help their opportune optimization to successfully reach the target.
Funder
Centre National de la Recherche Scientifique
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00669J
Reference41 articles.
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4. Current trends in the use of liposomes for tumor targeting
5. The role of liposomes in clinical nanomedicine development. What now? Now what?
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