Copper–TEMPO-catalyzed synthesis of α-ketoamides via tandem sp3C–H aerobic oxidation and amination of phenethyl alcohol derivatives-Reference-Cited by-同舟云学术

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Copper–TEMPO-catalyzed synthesis of α-ketoamides via tandem sp3C–H aerobic oxidation and amination of phenethyl alcohol derivatives

Published:2016 Issue:36 Volume:14 Page:8570-8575
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Chengkou¹²³,Yang Zhao⁴²³,Guo Shiyu¹²³,Zeng Yu¹²³,Zhu Ning¹²³,Li Xin¹²³,Fang Zheng¹²³,Guo Kai¹²³⁵⁶^ORCID

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering Nanjing Tech University 30 Puzhu South Road

2. Nanjing

3. China

4. College of Engineering China Pharmaceutical University

5. State Key Laboratory of Materials-Oriented Chemical Engineering Nanjing Tech

6. University

Abstract

The first synthesis of α-ketoamides from phenethyl alcohol derivatives, simple and readily available substrates, was achieved.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB01387B

Reference54 articles.

1. Design, Synthesis, and Biological Evaluation of Isoquinoline-1,3,4-trione Derivatives as Potent Caspase-3 Inhibitors

2. Synthesis of di- and tripeptide analogues containing α-ketoamide as a new core structure for inhibition of HIV-1 protease

3. Selectivity in the Inhibition of HIV and FIV Protease: Inhibitory and Mechanistic Studies of Pyrrolidine-Containing .alpha.-Keto Amide and Hydroxyethylamine Core Structures

4. Novel Peptidyl α-Keto Amide Inhibitors of Calpains and Other Cysteine Proteases

5. Macrocyclic Peptide Inhibitors of Serine Proteases. Convergent Total Synthesis of Cyclotheonamides A and B via a Late-Stage Primary Amine Intermediate. Study of Thrombin Inhibition under Diverse Conditions. [Erratum to document cited in CA122:161323]

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1. I₂‐Mediated Oxidative Amidation of Aryl Methyl Ketones: Synthesis of Primary α‐Ketoamides Using Ammonium Carbamodithioate as Amine Surrogate;European Journal of Organic Chemistry;2023-04-27

2. Copper‐Catalyzed Oxidative Amidation for the Synthesis of α‐Ketoamides from α‐Diazoketones with Amines Using Oxygen as Oxidant;Asian Journal of Organic Chemistry;2022-07-09

3. One-Pot Synthesis of α-Ketoamides from α-Keto Acids and Amines Using Ynamides as Coupling Reagents;The Journal of Organic Chemistry;2022-01-14

4. C-H Functionalization and C-N Bond Formation Approaches under Catalytic Conditions for the Synthesis of α-Ketoamides and 2,4-Disubstituted-1,3,5-triazines;Asian Journal of Chemistry;2022

5. Copper-Mediated Synthesis of Aryl α-Keto Amides from Epoxide Derivatives;Synlett;2020-03-03

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