In vitro antiproliferative effect of vanadium complexes bearing 8-hydroxyquinoline-based ligands – the substituent effect

Author:

Choroba Katarzyna1234ORCID,Raposo Luis R.56789ORCID,Palion-Gazda Joanna1234ORCID,Malicka Ewa1234,Erfurt Karol1011124,Machura Barbara1234ORCID,Fernandes Alexandra R.56789ORCID

Affiliation:

1. Institute of Chemistry

2. University of Silesia

3. 40-006 Katowice

4. Poland

5. UCIBIO

6. Departamento de Ciências da Vida

7. Faculdade de Ciências e Tecnologia

8. Universidade NOVA de Lisboa

9. 2829-516 Caparica

10. Department of Chemical Organic Technology and Petrochemistry

11. Silesian University of Technology

12. 44-100 Gliwice

Abstract

This is the first comprehensive study demonstrating the antiproliferative effect of vanadium complexes bearing 8-hydroxyquinoline (quinH) ligands, including the parent and –CH3 (Me), –NO2, –Cl and –I substituted ligands, on HCT116 and A2780 cancer cell lines.

Funder

Fundação para a Ciência e a Tecnologia

Ministério da Ciência, Tecnologia e Ensino Superior

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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