Albumin-driven disassembly of lipidic nanoparticles: the specific case of the squalene-adenosine nanodrug-Reference-Cited by-同舟云学术

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Albumin-driven disassembly of lipidic nanoparticles: the specific case of the squalene-adenosine nanodrug

Published:2020 Issue:4 Volume:12 Page:2793-2809
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Gobeaux Frédéric¹²³⁴⁵^ORCID,Bizeau Joëlle¹²³⁴⁵,Samson Firmin¹²³⁴⁵,Marichal Laurent¹²³⁴⁵^ORCID,Grillo Isabelle⁶⁷⁵^ORCID,Wien Frank⁸⁹⁵^ORCID,Yesylevsky Semen O.¹⁰¹¹¹²¹³^ORCID,Ramseyer Christophe¹⁴¹⁵¹⁶⁵,Rouquette Marie¹⁷¹⁸²¹⁹³,Lepêtre-Mouelhi Sinda¹⁷¹⁸²¹⁹³,Desmaële Didier¹⁷¹⁸²¹⁹³^ORCID,Couvreur Patrick¹⁷¹⁸²¹⁹³^ORCID,Guenoun Patrick¹²³⁴⁵^ORCID,Renault Jean-Philippe¹²³⁴⁵^ORCID,Testard Fabienne¹²³⁴⁵^ORCID

Affiliation:

1. LIONS – NIMBE CEA

2. CNRS

3. Université Paris-Saclay

4. 91191 Gif-sur-Yvette Cedex

5. France

6. Institut Laue Langevin

7. 38042 Grenoble Cedex 9

8. SOLEIL Synchrotron

9. Saint Aubin

10. Department of Physics of Biological Systems

11. Institute of Physics of the National Academy of Sciences of Ukraine

12. 03028 Kyiv

13. Ukraine

14. Laboratoire Chrono Environnement UMR CNRS 6249

15. Université de Bourgogne Franche-Comté

16. 25030 Besançon Cedex

17. Institut Galien Paris-Sud

18. UMR 8612

19. Université Paris-Sud

Abstract

Albumin forms a complex with the squalene-adenosine prodrug and by doing so drives the disassembly of the squalene-adenosine nanoparticles.

Funder

Agence Nationale de la Recherche

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/C9NR06485K

Reference87 articles.

1. Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects

2. Doxil® — The first FDA-approved nano-drug: Lessons learned

3. Aggregation of biopharmaceuticals in human plasma and human serum

4. T. Arvinte , Aggregation of Therapeutic Proteins after Mixing with Human Plasma: Implications for Drug Development , 2014

5. Evaluation of Nanoparticle Aggregation in Human Blood Serum

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4. Selective delivery of pentamidine toward cancer cells by self-assembled nanoparticles;International Journal of Pharmaceutics;2022-09

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