Efficient in vivo siRNA delivery by stabilized d-peptide-based lipid nanoparticles
Author:
Affiliation:
1. School of Chemistry & Chemical Engineering
2. Inner Mongolia University
3. Hohhot
4. PR China
Abstract
A lipid functionalized d-dipeptide has shown remarkable biocompatibility and tissue targeting as well as excellent RNAi delivery efficiency in vivo.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA25862J
Reference30 articles.
1. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2. siRNA function in RNAi: A chemical modification analysis
3. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
4. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
5. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
Cited by 13 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Optimized lipid nanoparticles (LNPs) for organ-selective nucleic acids delivery in vivo;iScience;2024-06
2. Oral Delivery of SARS-CoV-2 DNA Vaccines Using Attenuated Salmonella typhimurium as a Carrier in Rat;Molecular Genetics, Microbiology and Virology;2022-09
3. Peptidomimetic Lipid-Nanoparticle-Mediated Knockdown of TLR4 in CNS Protects against Cerebral Ischemia/Reperfusion Injury in Mice;Nanomaterials;2022-06-16
4. Trends and Hotspots in Nanoparticles for the Targeted Delivery of Nucleic Acids: A Ten-Year Bibliometric Study;Frontiers in Pharmacology;2022-05-04
5. Regulation of microglia polarization via mannose receptor-mediated delivery of siRNA by ligand-functionalized DoGo LNP;RSC Advances;2021
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3