β-Carboline directed regioselective hydroxylation by employing Cu(OAc)2 and mechanistic investigation by ESI-MS-Reference-Cited by-同舟云学术

β-Carboline directed regioselective hydroxylation by employing Cu(OAc)2 and mechanistic investigation by ESI-MS

Published:2020 Issue:12 Volume:18 Page:2307-2311
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Bora Darshana¹²³⁴,Tokala Ramya¹²³⁴,John Stephy Elza¹²³⁴,Prasanth Bitla¹²³⁴,Shankaraiah Nagula¹²³⁴^ORCID

Affiliation:

1. Department of Medicinal Chemistry

2. National Institute of Pharmaceutical Education and Research (NIPER)

3. Hyderabad-500037

4. India

Abstract

This protocol demonstrates microwave-irradiated monohydroxylation on different heterocycles via C–H functionalization which leads into the development of biologically relevant molecules.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00250J

Reference42 articles.

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3. Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma

4. Synthesis and in vitro cytotoxicity evaluation of β-carboline-linked 2,4-thiazolidinedione hybrids: potential DNA intercalation and apoptosis-inducing studies

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