Development of nanoelectrospray high resolution isotope dilution mass spectrometry for targeted quantitative analysis of urinary metabolites: application to population profiling and clinical studies

Author:

Chekmeneva Elena12345,Correia Gonçalo12345,Dénes Júlia12345,Gómez-Romero María12345,Wijeyesekera Anisha12345,Perenyi Dora R.12345,Koot Yvonne67,Boomsma Carolien67,Want Elisabeth. J.12345,Dixon Peter H.859,Macklon Nicholas S.67109,Chan Queenie11125139,Takáts Zoltán12345,Nicholson Jeremy K.12345,Holmes Elaine12345

Affiliation:

1. Biomolecular Medicine

2. Section of Computational and Systems Medicine

3. Department of Surgery and Cancer

4. Faculty of Medicine

5. Imperial College London

6. Utrecht University

7. The Netherlands

8. Institute of Reproductive and Developmental Biology

9. UK

10. University of Southampton

11. Department of Epidemiology and Biostatistics

12. School of Public Health

13. London W2 1PG

Abstract

An automated nESI-HRMS method for targeted quantitative analysis and global metabolic profiling of urine samples.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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