Synthesis of multi-substituted pyridines from ylidenemalononitriles and their emission properties

Author:

de Souza Juliana M.12345,Abdiaj Irini1234,Chen Jiaqi6784,Hanson Kenneth6784ORCID,de Oliveira Kleber T.591011ORCID,McQuade D. Tyler1234

Affiliation:

1. Department of Chemical and Life Science Engineering

2. Virginia Commonwealth University

3. Richmond

4. USA

5. Departamento de Química

6. Department of Chemistry & Biochemistry

7. Florida State University

8. Tallahassee

9. Universidade Federal de São Carlos

10. São Carlos

11. Brazil

Abstract

A mild and solvent-free methodology to obtain a scope of multi-substituted pyridines at room temperature is presented. One of the resulting amino-nicotinonitriles exhibits a preliminary evidence of aggregation-induced emission (AIE).

Funder

National Institutes of Health

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference44 articles.

1. P. Kiuru and J.Yli-Kauhaluoma , in Heterocycles in Natural Product Synthesis , ed. K. C. Majumdar and S. K. Chattopadhyay , Wiley–VCH Verlag GmbH & Co. , 2011 , pp. 267–297

2. F. Yates , R. T.Courts and A. F.Casy , in Pyridine and Its Derivatives; supplement IV , ed. R. A. Abramovitch , Wiley , New York , 1975 , p. 445

3. E. F. V. Scriven , Pyridines: from Lab to Production , Elsevier , Amsterdam , 1st edn, 2013

4. Investigating the continuous synthesis of a nicotinonitrile precursor to nevirapine

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