Pharmaceutical polymorph control in a drug-mimetic supramolecular gel

Author:

Foster Jonathan A.1234ORCID,Damodaran Krishna K.15678,Maurin Antoine19104,Day Graeme M.1112134ORCID,Thompson Hugh P. G.114154,Cameron Gary J.19104,Bernal Jenifer Cuesta19104,Steed Jonathan W.19104ORCID

Affiliation:

1. Department of Chemistry

2. University of Sheffield

3. Sheffield

4. UK

5. Science Institute

6. University of Iceland

7. 107 Reykjavík

8. Iceland

9. Durham University

10. Durham

11. School of Chemistry

12. University of Southampton

13. Southampton

14. University of Cambridge

15. Cambridge

Abstract

A supramolecular gel designed to chemically mimic the structure of a pharmaceutical compound controls the polymorphic outcome of the crystallization of the substrate.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Reference58 articles.

1. R. Hilfiker , Polymorphism: In the Pharmaceutical Industry, Wiley-VCH, Weinheim, 2006

2. A practical guide to pharmaceutical polymorph screening & selection

3. Polymorphism in Pharmaceutical Solids, ed. H. G. Brittain, Marcel Dekker Inc., New York, 1999

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