The nanomechanical signature of liver cancer tissues and its molecular origin-Reference-Cited by-同舟云学术

The nanomechanical signature of liver cancer tissues and its molecular origin

Published:2015 Issue:30 Volume:7 Page:12998-13010
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Tian Mengxin¹²³⁴⁵,Li Yiran⁶⁷⁸,Liu Weiren¹²³⁴⁵,Jin Lei¹²³⁴⁵,Jiang Xifei¹²³⁴⁵,Wang Xinyan⁹¹⁰¹¹¹²¹³,Ding Zhenbin¹²³⁴⁵,Peng Yuanfei¹²³⁴⁵,Zhou Jian¹²³⁴⁵,Fan Jia¹²³⁴⁵,Cao Yi⁶⁷⁸,Wang Wei⁶⁷⁸,Shi Yinghong¹²³⁴⁵

Affiliation:

1. Department of Liver Surgery

2. Liver Cancer Institute

3. Zhongshan Hospital

4. Fudan University

5. Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education

6. Collaborative Innovation Center of Advanced Microstructures

7. National Laboratory of Solid State Microstructure and Department of Physics

8. Nanjing 210093, P.R. China

9. National Center for Protein Science Shanghai (NCPSS)

10. Institute of Biochemistry and Cell Biology (SIBCB)

11. Shanghai Institutes for Biological Sciences (SIBS)

12. Chinese Academy of Sciences (CAS)

13. Shanghai, China

Abstract

Hepatocarcinogenesis is a complicated multistep process with abnormalities in the nanomechanics and structures. When disease is progressing, the stiffness distribution across liver tissue alters with specific nanomechanical profiles.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NR/C5NR02192H

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