Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis-Reference-Cited by-同舟云学术

Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis

Published:2020 Issue:16 Volume:8 Page:4467-4480
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Stasiak Joanna R.¹²³⁴^ORCID,Serrani Marta¹²³⁴,Biral Eugenia¹²³⁴,Taylor James V.⁵²³⁴,Zaman Azfar G.⁶⁷⁸⁹⁴,Jones Samantha¹⁰¹¹⁹⁴,Ness Thomas¹²¹³⁹⁴,De Gaetano Francesco¹⁴¹⁵¹⁶¹⁷¹⁸,Costantino Maria Laura¹⁴¹⁵¹⁶¹⁷¹⁸,Bruno Vito D.¹⁹²⁰²¹⁴,Suleiman Saadeh¹⁹²⁰²¹⁴^ORCID,Ascione Raimondo¹⁹²⁰²¹⁴,Moggridge Geoff D.¹²³⁴

Affiliation:

1. Department of Chemical Engineering and Biotechnology

2. University of Cambridge

3. Cambridge

4. UK

5. Department of Engineering

6. Cardiology

7. Freeman Hospital and Institute of Cellular Medicine

8. Newcastle University

9. Newcastle upon Tyne

10. Cardiology Research

11. Newcastle upon Tyne NHS Hospitals Trust

12. Newcastle Molecular Pathology Node

13. Newcastle upon Tyne Hospitals NHS Hospitals Trust

14. Department of Chemistry

15. Materials and Chemical Engineering “Giulio Natta”

16. Politecnico di Milano

17. Milano

18. Italy

19. Bristol Heart Institute and Translational Biomedical Research Centre

20. University of Bristol

21. Bristol

Abstract

A novel polymeric heart valve shows durability equivalent to 25 years in accelerated bench testing, in vitro hydrodynamics equivalent to existing bioprosthetic valves; and good performance in a small acute feasibility study in sheep.

Funder

British Heart Foundation

Medical Research Council

Royal Academy of Engineering

Leverhulme Trust

King's College Cambridge, University of Cambridge

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00412J