Synthesis and biological evaluation of novel fluorinated anticancer agents incorporating the indolin-2-one moiety

Author:

Wang Shuai-Yu1234,Wang Li-Jun1234,Jiang Bo1234,Wu Ning1234,Li Xiang-Qian1234,Luo Jiao1234,Wang Bao-Cheng1234,Zhang Ren-Shuai1234,Xu Qi1234,Shi Da-Yong1234

Affiliation:

1. Key Laboratory of Experimental Marine Biology

2. Institute of Oceanology

3. Chinese Academy of Sciences

4. China

Abstract

A series of novel fluorinated anticancer agents containing the indolin-2-one moiety were designed, synthesized and evaluated for their anticancer activities in vitro.

Funder

China Postdoctoral Science Foundation

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference22 articles.

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2. Synthesis and biological evaluation of novel shikonin ester derivatives as potential anti-cancer agents

3. Synthesis and evaluation of the antitumor activity of polyhalo acridone derivatives

4. Synthesis and biological evaluation of peptidomimetics containing the tryptamine moiety as a potential antitumor agent

5. Synthesis, in vitro anticancer activity and SAR studies of arylated imidazo[1,2-a]pyrazine–coumarin hybrids

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