Palladium-catalyzed ortho-selective C–H hydroxylation of carboxybenzyl-protected benzylamines-Reference-Cited by-同舟云学术

Palladium-catalyzed ortho-selective C–H hydroxylation of carboxybenzyl-protected benzylamines

Published:2020 Issue:13 Volume:7 Page:1703-1708
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Dai Chenyang¹²³⁴⁵,Han Yi¹²³⁴⁵,Liu Lingling¹²³⁴⁵,Huang Zhi-Bin¹²³⁴⁵,Shi Da-Qing¹²³⁴⁵^ORCID,Zhao Yingsheng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Organic Synthesis of Jiangsu Province

2. College of Chemistry

3. Chemical Engineering and Materials Science

4. Soochow University

5. Suzhou 215123

Abstract

A convenient approach to synthesize o-hydroxybenzylamine via Pd-catalyzed hydroxylation of benzylamine with a removable Cbz-amide as the directing group was developed.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/C9QO01523J

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5. Palladium-catalysed hydroxylation and alkoxylation

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