A pH/GSH dual responsive nanoparticle with relaxivity amplification for magnetic resonance imaging and suppression of tumors and metastases-Reference-Cited by-同舟云学术

A pH/GSH dual responsive nanoparticle with relaxivity amplification for magnetic resonance imaging and suppression of tumors and metastases

Published:2023 Issue:4 Volume:15 Page:1583-1594
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zhu Xianglong¹^ORCID,Xiong Hehe²,Yang Pei¹,Wang Songwei³,Zhou Qiuju³,Zhang Pengbo¹^ORCID,Zhao Zhenghuan⁴^ORCID,Shi Saige¹^ORCID

Affiliation:

1. School of Public Health, Xinxiang Medical University, Xinxiang 453003, China

2. School of Public Health, Xiamen University, Xiamen 361102, China

3. Analysis Testing Center, Xinyang Normal University, Xinyang 464000, China

4. College of Basic Medicine, Chongqing Medical University, Chongqing 400716, China

Abstract

We report an intelligent theranostic nanoprobe based on Mn3O4 tetragonal bipyramids, which boost MRI relaxivity and chemodynamic capacity upon simultaneous responding to H+ and GSH, for precise diagnosis and suppression of solid tumor and metastasis.

Funder

Chongqing University

Chongqing Medical University

Xinxiang Medical University

Science and Technology Department of Henan Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NR/D2NR05449C