A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives-Reference-Cited by-同舟云学术

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A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives

Published:2019 Issue:9 Volume:10 Page:5510-5520
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Rocha Sónia¹²³⁴⁵,Sousa Adelaide¹²³⁴⁵,Ribeiro Daniela¹²³⁴⁵,Correia Catarina M.⁶⁷⁸⁹¹⁰,Silva Vera L. M.⁶⁷⁸⁹¹⁰^ORCID,Santos Clementina M. M.⁶⁷⁸⁹¹⁰,Silva Artur M. S.⁶⁷⁸⁹¹⁰^ORCID,Araújo Alberto N.¹²³⁴⁵,Fernandes Eduarda¹²³⁴⁵^ORCID,Freitas Marisa¹²³⁴⁵^ORCID

Affiliation:

1. LAQV

2. REQUIMTE

3. Laboratory of Applied Chemistry

4. Department of Chemical Sciences

5. Faculty of Pharmacy

6. QOPNA & LAQV-REQUIMTE

7. Department of Chemistry

8. University of Aveiro

9. Aveiro

10. Portugal

Abstract

Butein, a competitive inhibitor of α-amylase and α-glucosidase enzymes, is a promising therapeutic drug to modulate diabetes mellitus.

Funder

European Regional Development Fund

Fundação para a Ciência e a Tecnologia

Ministério da Educação e Ciência

Universidade de Aveiro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/FO/C9FO01298B

Reference50 articles.

1. International Diabetes Federation , IDF Diabetes atlas , 2017

2. Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management

3. Type 2 diabetes mellitus

4. Postprandial Blood Glucose

5. New forms of insulin and insulin therapies for the treatment of type 2 diabetes

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