Ruthenium-catalyzed asymmetric hydrogenation of aromatic and heteroaromatic ketones using cinchona alkaloid-derived NNP ligands-Reference-Cited by-同舟云学术

Ruthenium-catalyzed asymmetric hydrogenation of aromatic and heteroaromatic ketones using cinchona alkaloid-derived NNP ligands

Published:2022 Issue:23 Volume:12 Page:14912-14916
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhang Ling¹,Chen Qian¹,Li Linlin¹,Jiang Jian¹,Sun Hao¹,Li Li¹,Liu Ting¹,Zhang Lin¹,Li Chun¹^ORCID

Affiliation:

1. State Key Laboratory of Functions and Applications of Medicinal Plants & School of Pharmaceutical Sciences, Guizhou Medical University, 550004 Guiyang, China

Abstract

A series of cinchona alkaloid-based NNP ligands including a new one has been employed for the asymmetric hydrogenation of ketones. By combining ruthenium complexes, various ketones were smoothly reacted with up to 99.9% ee.

Funder

National Natural Science Foundation of China

Science and Technology Program of Guizhou Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02211G

Reference67 articles.

1. Asymmetric Hydrogenation of Aromatic Ketones Catalyzed by the TolBINAP/DMAPEN−Ruthenium(II) Complex: A Significant Effect of N-Substituents of Chiral 1,2-Diamine Ligands on Enantioselectivity

2. Highly Efficient and Highly Enantioselective Asymmetric Hydrogenation of Ketones with TunesPhos/1,2-Diamine−Ruthenium(II) Complexes

3. General Asymmetric Hydrogenation of Hetero-aromatic Ketones

4. The Synthesis of Chiral Phosphorus Ligands for use in Homogeneous Metal Catalysis

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