Synthesis and biological evaluation of N-(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents-Reference-Cited by-同舟云学术

Synthesis and biological evaluation of N-(4-phenylthiazol-2-yl)cinnamamide derivatives as novel potential anti-tumor agents

Published:2015 Issue:6 Volume:6 Page:1036-1042
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Luo Yong¹²³⁴¹,Zhu Yongxia¹²³⁴¹,Ran Kai¹²³⁴¹,Liu Zhihao¹²³⁴¹,Wang Ningyu¹²³⁴¹,Feng Qiang¹²³⁴¹,Zeng Jun¹²³⁴¹,Zhang Lidan⁵⁶¹⁷⁸,He Bing¹²³⁴¹,Ye Tinghong¹²³⁴¹,Zhu Shirui⁹¹⁰¹¹¹²⁸,Qiu Xiaolong¹³¹⁴⁸,Yu Luoting¹²³⁴¹

Affiliation:

1. Sichuan University

2. State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center

3. West China Hospital

4. West China Medical School

5. Department of Pharmaceutical and Bioengineering

6. School of Chemical Engineering

7. Chengdu

8. China

9. Department of Encephalopathy

10. The First Affiliated Hospital of Henan University of Traditional Chinese Medicine

11. Henan University of Traditional Chinese Medicine

12. Zhengzhou

13. Wisdom Pharmaceutical Co. Ltd

14. Haimen

Abstract

In this study, a series of novel N-(4-phenylthiazol-2-yl)-cinnamamide derivatives (7a–8n) were synthesized and evaluated for their anti-proliferative activities in vitro.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00573B

Reference26 articles.

1. Cancer statistics, 2014

2. An Update on Overcoming MDR1-Mediated Multidrug Resistance in Cancer Chemotherapy

3. Editorial (Thematic Issue: Signalling Pathways in Anti-cancer Drug Resistance)

4. Cell Death

5. Apoptosis in the Pathogenesis and Treatment of Disease

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