The systematic characterization of multiple components and metabolic profiling of bioactive constituents in Yaobitong capsule by UHPLC/Q-TOF-MS/MS-Reference-Cited by-同舟云学术

The systematic characterization of multiple components and metabolic profiling of bioactive constituents in Yaobitong capsule by UHPLC/Q-TOF-MS/MS

Published:2021 Issue:46 Volume:13 Page:5589-5607
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Bai Shuru¹,Li Xianhui¹,Wang Zhenzhong²³,Xiao Wei²³,Zhao Longshan¹^ORCID

Affiliation:

1. School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, 110016, Shenyang, Liaoning Province, P. R. China

2. Jiangsu Kanion Pharmaceutical Co. Ltd., Lianyungang, 222001, China

3. State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Lianyungang 222001, Jiangsu, China

Abstract

A rapid and reliable UHPLC-Q-TOF-MS/MS method was successfully established to analyze the complex compounds in Yaobitong capsule and analyze their absorption states in biological samples, including urine, feces, and bile, after the oral administration of Yaobitong capsule.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D1AY01564H

Reference37 articles.

1. Systems Pharmacology Based Strategy for Q-Markers Discovery of HuangQin Decoction to Attenuate Intestinal Damage

2. Systems Biology Technologies Enable Personalized Traditional Chinese Medicine: A Systematic Review

3. Bioactive Equivalence of Combinatorial Components Identified in Screening of an Herbal Medicine

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