Portable immunosensor directly and rapidly detects Mycobacterium tuberculosis in sputum

Author:

Ma Jinbiao12ORCID,Jiang Guanyu12,Ma Qingqing3,Du Manman12,Wang Hao45,Wu Jianguo45,Wang Can12ORCID,Xie Xinwu46ORCID,Li Tie78,Chen Shixing78,Zhang Lixia9,Wu Min9

Affiliation:

1. School of Environmental Science and Engineering, Tianjin University, Tianjin, 300072, PR China

2. Tianjin Key Lab of Indoor Air Environmental Quality Control, Tianjin, 300072, PR China

3. Department of Respiratory Medicine, Shandong Public Health Clinical Center (Shandong Province Chest Hospital), Jinan, 250013, PR China

4. Institute of Medical Support Technology, Academy of Military Science, Tianjin, 300161, PR China

5. School of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin, 300222, PR China

6. National Bio-Protection Engineering Center, Tianjin, 300161, PR China

7. Science and Technology on Micro-system Laboratory, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, PR China

8. State Key Laboratories of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai, 200050, PR China

9. Tianjin Haihe Hospital, Tianjin, 300350, PR China

Abstract

The immunosensor can complete the sputum detection directly within a few minutes, which greatly shortens the diagnosis time of TB.

Funder

National Science and Technology Major Project

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference43 articles.

1. World Health Organization , Global Tuberculosis Report , 2020 , https://www.who.int/teams/global-tuberculosisprogramme/data (Update 14 Oct 2020)

2. CDC , Basic TB Facts. (ONLINE) , 2016 , http://www.cdc.gov/tb/topic/basics/

3. Recent technological advancements in tuberculosis diagnostics – A review

4. The overview and perspectives of biosensors and Mycobacterium tuberculosis : A systematic review

5. Rapid culture-based diagnosis of pulmonary tuberculosis in developed and developing countries

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