A nuclear targeted dual-photosensitizer for drug-resistant cancer therapy with NIR activated multiple ROS-Reference-Cited by-同舟云学术

A nuclear targeted dual-photosensitizer for drug-resistant cancer therapy with NIR activated multiple ROS

Published:2016 Issue:7 Volume:7 Page:4237-4244
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yu Zhengze¹²³⁴⁵,Pan Wei¹²³⁴⁵,Li Na¹²³⁴⁵,Tang Bo¹²³⁴⁵

Affiliation:

1. College of Chemistry

2. Chemical Engineering and Materials Science

3. Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong

4. Key Laboratory of Molecular and Nano Probes

5. Ministry of Education

Abstract

A nuclear targeted dual-photosensitizer was developed for photodynamic therapy against multidrug resistant cancer. Multiple reactive oxygen species (ROS) could be generated in the nucleus to directly break DNA double strands with a single 980 nm NIR laser irradiation, regardless of drug resistance.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00737F

Reference44 articles.

1. World Health Organization , The Global Burden of Disease, 2004 Update, World Health Organization, Geneva, 2008

2. Global cancer statistics

3. Photodynamic therapy for cancer

4. Functional Nanomaterials for Phototherapies of Cancer

Cited by 163 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Subcellular Drug Distribution: Exploring Organelle-Specific Characteristics for Enhanced Therapeutic Efficacy;Pharmaceutics;2024-09-04

2. Targeting tumor microenvironment with photodynamic nanomedicine;Medicinal Research Reviews;2024-08-16

3. Light Emitting Rare Earth Doped K₃GdF₆:Eu³⁺ for Spectral Mapping/Imaging Studies;ACS Applied Optical Materials;2024-08-03

4. A bioactive nanocomposite integrated specific TAMs target and synergistic TAMs repolarization for effective cancer immunotherapy;Bioactive Materials;2024-08

5. Porphyrins—valuable pigments of life;Frontiers in Chemical Biology;2024-01-10