Ginseng oligosaccharides protect neurons from glutamate-induced oxidative damage through the Nrf2/HO-1 signaling pathway-Reference-Cited by-同舟云学术

Ginseng oligosaccharides protect neurons from glutamate-induced oxidative damage through the Nrf2/HO-1 signaling pathway

Published:2022 Issue:16 Volume:13 Page:8605-8615
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yan Xiuci¹,Chen Xuenan¹,Fu Chunge²,Jing Chenxu¹,Zhao Daqing³,Sun Liwei¹⁴^ORCID

Affiliation:

1. Research Center of Traditional Chinese Medicine, the Affiliated Hospital to Changchun University of Chinese Medicine, 1478 Gongnong Street, Changchun, Jilin Province, 130021, PR China

2. Changchun Maternal and Child Health Care Center, Changchun, 1287 Dama Road, Changchun, Jilin Province 130021, PR China

3. Jilin Ginseng Academy, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun, Jilin Province 130021, PR China

4. Jilin Provincial Science and Technology Innovation Cross-Regional Cooperation Center of Traditional Chinese Medicine Health Product Research and Development, PR China

Abstract

In our study, the oligosaccharide fraction was obtained from ginseng, and its neuroprotective efficacy was demonstrated. Furthermore, the efficacy mechanism of ginseng oligosaccharides may be related to the Nrf2/HO-1 signaling pathway.

Funder

Administration of Traditional Chinese Medicine of Jilin Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01432G

Reference40 articles.

1. Role of metabotropic glutamate receptors in the control of neuroendocrine function

2. Glutamate receptors, neurotoxicity and neurodegeneration

3. Protective Effect of Osmundacetone against Neurological Cell Death Caused by Oxidative Glutamate Toxicity

4. Effects of Panax ginseng in Neurodegenerative Diseases

5. Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats

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