Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays-Reference-Cited by-同舟云学术

Discovery of hCES2A inhibitors from Glycyrrhiza inflata via combination of docking-based virtual screening and fluorescence-based inhibition assays

Published:2021 Issue:1 Volume:12 Page:162-176
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Song Yun-Qing¹²³⁴,Guan Xiao-Qing¹²³⁴,Weng Zi-Miao⁵⁶⁷⁸⁴,Liu Jun-Ling¹²³⁴,Chen Jing¹²³⁴,Wang Lu¹²³⁴,Cui Long-Tao⁹²³⁴,Fang Sheng-Quan¹⁰²³⁴,Hou Jie⁵⁶⁷⁸⁴^ORCID,Ge Guang-Bo¹²³⁴¹⁰^ORCID

Affiliation:

1. Institute of Interdisciplinary Integrative Medicine Research

2. Shanghai University of Traditional Chinese Medicine

3. Shanghai

4. China

5. Department of Biotechnology

6. College of Basic Medical Sciences

7. Dalian Medical University

8. Dalian 116044

9. Basic Medical College

10. Yueyang Hospital of Integrated Traditional Chinese and Western Medicine

Abstract

An integrated strategy via combination of chemical profiling, docking-based virtual screening and fluorescence-based high-throughput inhibitor screening assays was used to efficiently identify natural hCES2A inhibitors from herbal medicines.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Liaoning Province

Program of Shanghai Academic Research Leader

Dalian High-Level Talent Innovation Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02140G

Reference53 articles.