Two-layer cascaded catalytic hairpin assemblies based on locked nucleic acids for one-step and highly sensitive ctDNA detection-Reference-Cited by-同舟云学术

Two-layer cascaded catalytic hairpin assemblies based on locked nucleic acids for one-step and highly sensitive ctDNA detection

Published:2024 Issue:22 Volume:16 Page:3515-3521
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Tan Kaiyue¹²³,Chen Longsheng¹²³,Cao Donglin⁴,Xiao Wei⁴,Lv Qian¹²³,Zou Lili¹²³^ORCID

Affiliation:

1. National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, China

2. Guangdong Engineering Technology Research Center for Diagnosis and Rehabilitation of Dementia, Guangzhou 510316, China

3. Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Polymer Material Products, Guangzhou 510316, China

4. Department of Laboratory Medicine, Guangdong Provincial Key Laboratory of Point-of-Care Testing (POCT), Guangdong Second Provincial General Hospital, Guangzhou, 510500, China

Abstract

Enzyme-free signal amplification of catalytic hairpin assembly (CHA) has enabled sensitive detection of circulating tumor DNA (ctDNA) in early clinical diagnosis.

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

Guangdong Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D4AY00611A

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