A simple three-dimensional gut model constructed in a restricted ductal microspace induces intestinal epithelial cell integrity and facilitates absorption assays
Author:
Affiliation:
1. Institute of Industrial Science
2. The University of Tokyo
3. Tokyo 153-8505
4. Japan
5. Sumitomo Chemical
6. Co.
7. Ltd.
8. Tokyo 104-8260
Abstract
A new 3D gut-on-a-chip on a ductal scaffold induced a differentiated epithelial layer and allowed permeability and absorption assay.
Funder
Japan Society for the Promotion of Science
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering
Link
http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00763C
Reference55 articles.
1. Morphogenesis and maturation of the embryonic and postnatal intestine
2. Impact of the gut microbiota on inflammation, obesity, and metabolic disease
3. Gut Wall Metabolism. Application of Pre-Clinical Models for the Prediction of Human Drug Absorption and First-Pass Elimination
4. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
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