Riboflavin–citrate conjugate multicore SPIONs with enhanced magnetic responses and cellular uptake in breast cancer cells

Author:

Mekseriwattana Wid12ORCID,Guardia Pablo2,Herrero Beatriz Torres3ORCID,de la Fuente Jesus M.3,Kuhakarn Chutima4ORCID,Roig Anna2ORCID,Katewongsa Kanlaya Prapainop15ORCID

Affiliation:

1. School of Materials Science and Innovation, Faculty of Science, Mahidol University, Bangkok 10400, Thailand

2. Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus UAB, Bellaterra 08193, Spain

3. Instituto de Nanociencia y Materiales de Aragón (INMA), CSIC-Universidad de Zaragoza, Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), 50018 Zaragoza, Spain

4. Department of Chemistry, Center of Exellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10400, Thailand

5. Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok 10400, Thailand

Abstract

Riboflavin-coated multicore SPIONs show specific binding with RCP, enhanced uptake in breast cancer cells and excellent MRI response.

Funder

Ministry of Higher Education, Science, Research and Innovation, Thailand

Faculty of Science, Mahidol University

National Research Council of Thailand

Mahidol University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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