Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation-Reference-Cited by-同舟云学术

Synthesis of conjugation-ready zwitterionic oligosaccharides by chemoselective thioglycoside activation

Published:2014 Issue:5 Volume:5 Page:1992-2002
ISSN:2041-6520
Container-title:Chem. Sci.
language:en
Short-container-title:Chem. Sci.

Author:

Schumann B.¹²³⁴,Pragani R.¹²,Anish C.¹²,Pereira C. L.¹²,Seeberger P. H.¹²³⁴

Affiliation:

1. Max Planck Institute of Colloids and Interfaces

2. 14424 Potsdam, Germany

3. Freie Universität Berlin

4. 14195 Berlin, Germany

Abstract

A method to chemoselectively activate thioglycosides in the presence of thioethers is developed and applied in the total synthesis of repeating units of S. pneumoniae Sp1 and B. fragilis PS A1. Biochemical evaluation of these glycans is performed after conjugation to reporter moieties.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/SC/C3SC53362J

Reference126 articles.

1. Role of glycan synthesis in colonization of the mammalian gut by the bacterial symbiont Bacteroides fragilis

2. S. Merino and J. M.Tomás , in Encyclopedia of Life Sciences (ELS) , John Wiley & Sons , Chichester , 2010

3. RELATION OF VIRULENCE OF PNEUMOCOCCAL STRAINS FOR MICE TO THE QUANTITY OF CAPSULAR POLYSACCHARIDE FORMED IN VITRO

4. Requirement for Capsule in Colonization by Streptococcus pneumoniae

5. The Capsular Polysaccharide of Burkholderia pseudomallei Contributes to Survival in Serum by Reducing Complement Factor C3b Deposition

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