The reactions of α-amino acids and α-amino acid esters with high valent transition metal halides: synthesis of coordination complexes, activation processes and stabilization of α-ammonium acylchloride cations

Author:

Biancalana Lorenzo1234,Bortoluzzi Marco5674,Ferretti Eleonora1234,Hayatifar Mohammad1234,Marchetti Fabio1234ORCID,Pampaloni Guido1234ORCID,Zacchini Stefano89104ORCID

Affiliation:

1. University of Pisa

2. Dipartimento di Chimica e Chimica Industriale

3. I-56124 Pisa

4. Italy

5. Ca' Foscari University of Venice

6. Dipartimento di Scienze Molecolari e Nanosistemi

7. I-30175 Mestre

8. University of Bologna

9. Dipartimento di Chimica Industriale “Toso Montanari”

10. I-40136 Bologna

Abstract

We describe the synthesis of rare coordination compounds of early transition metals with α-amino acids and α-amino acid esters, the unusual C–C dimerization ofl-proline, and the stabilization of reactive α-ammonium acylchloride cations.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference147 articles.

1. K. Drauz , I.Grayson, A.Kleemann, H.-P.Krimmer, W.Leuchtenberger and C.Weckbecker, Amino Acids, Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, Germany, 2012, vol. 3, pp. 1–58

2. K. Araki and T.Ozeki, Amino Acids, Kirk-Othmer Encyclopedia of Chemical Technology, John Wiley & Sons, Hoboken, NJ, USA, 5th edn, 2004, vol. 2, pp. 554–618

3. A new generation of chiral phase-transfer catalysts

4. Isotope Effects Reveal the Mechanism of Enamine Formation in l-Proline-Catalyzed α-Amination of Aldehydes

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