Supramolecular adducts between macrocyclic Gd(iii) complexes and polyaromatic systems: a route to enhance the relaxivity through the formation of hydrophobic interactions-Reference-Cited by-同舟云学术

Supramolecular adducts between macrocyclic Gd(iii) complexes and polyaromatic systems: a route to enhance the relaxivity through the formation of hydrophobic interactions

Published:2021 Issue:4 Volume:12 Page:1368-1377
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Di Gregorio Enza¹²³⁴⁵^ORCID,Lattuada Luciano⁶⁷⁸⁵^ORCID,Maiocchi Alessandro⁶⁷⁸⁵,Aime Silvio¹²³⁴⁵^ORCID,Ferrauto Giuseppe¹²³⁴⁵^ORCID,Gianolio Eliana¹²³⁴⁵^ORCID

Affiliation:

1. Molecular Imaging Center

2. Department of Molecular Biotechnologies and Health Sciences

3. University of Torino

4. Torino

5. Italy

6. Bracco Imaging Spa

7. Bracco Research Centre

8. Colleretto Giacosa

Abstract

The set-up of reversible binding interactions between the hydrophobic region of macrocyclic gadolinium based contrast agents and SO₃⁻/OH containing pyrene derivatives provides new insights for pursuing relaxivity enhancement of MRI contrast agents.

Funder

Regione Piemonte

Università degli Studi di Torino

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D0SC03504A

Reference46 articles.

1. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging , ed. A. Merbach , L. Helm and É. Tóth , Wiley , New York , 2nd edn, 2013

2. Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers