Delivering the cell-impermeable DNA ‘light-switching’ Ru(ii) complexes preferentially into live-cell nucleus via an unprecedented ion-pairing method-Reference-Cited by-同舟云学术

Delivering the cell-impermeable DNA ‘light-switching’ Ru(ii) complexes preferentially into live-cell nucleus via an unprecedented ion-pairing method

Published:2016 Issue:7 Volume:7 Page:4016-4023
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Zhu Ben-Zhan¹²³⁴⁵,Chao Xi-Juan¹²³⁴⁵,Huang Chun-Hua¹²³⁴⁵,Li Yan¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Environmental Chemistry and Ecotoxicology

2. Research Center for Eco-Environmental Sciences

3. The Chinese Academy of Sciences

4. Beijing

5. P. R. China 100085

Abstract

The cell-impermeable DNA ‘light-switching’ Ru(ii) complexes can be delivered into live-cell nucleus by forming lipophilic Yin–Yang ion-pairs with hydrophobic weak-acids.

Funder

National Institute of Environmental Health Sciences

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC03796D

Reference35 articles.

1. Fluorescent Labeling of Biomolecules with Organic Probes

2. Creating new fluorescent probes for cell biology

3. A molecular light switch for DNA: Ru(bpy)2(dppz)2+

4. Ruthenium(ii) polypyridyl complexes and DNA—from structural probes to cellular imaging and therapeutics

5. The path for metal complexes to a DNA target

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