Unexpectedly stable homopurine parallel triplex of SNA:RNA*SNA and <scp>l</scp>-<i>a</i>TNA:RNA*<scp>l</scp>-<i>a</i>TNA-Reference-Cited by-同舟云学术

Unexpectedly stable homopurine parallel triplex of SNA:RNA*SNA and l-aTNA:RNA*l-aTNA

Published:2024 Issue:10 Volume:60 Page:1257-1260
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Kamiya Yukiko¹²³^ORCID,Lao Siyuan¹,Ariyoshi Jumpei²,Sato Fuminori¹,Asanuma Hiroyuki¹^ORCID

Affiliation:

1. Department of Biomolecular Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan

2. Laboratory of Bioanalytical Chemistry, Kobe Pharmaceutical University, Higashinada-Ku, Kobe, 658-8558, Japan

3. Institute for Molecular Science, National Institutes of Natural Sciences, Okazaki, Aichi 444-8585, Japan

Abstract

We first report parallel triplex formation between a homopurine SNA (l-aTNA) strand and an RNA/SNA (l-aTNA) duplex. Melting profiles revealed that the parallel triplex was remarkably stable, even though A*A pair has a single hydrogen bond.

Funder

Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences

Japan Agency for Medical Research and Development

Inamori Foundation

Japan Society for the Promotion of Science

Nagoya University

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D3CC05555H

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