Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast cancer-Reference-Cited by-同舟云学术

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Enhanced drug internalization and therapeutic efficacy of PEGylated nanoparticles by one-step formulation with anti-mPEG bispecific antibody in intrinsic drug-resistant breast cancer

Published:2019 Issue:8 Volume:7 Page:3404-3417
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Cheng Yi-An¹²³⁴^ORCID,Chen I-Ju⁵²³⁴^ORCID,Su Yu-Cheng⁶⁷⁸⁴,Cheng Kai-Wen⁵²³⁴,Lu Yun-Chi¹²³⁴^ORCID,Lin Wen-Wei¹²³⁴⁵^ORCID,Hsieh Yuan-Chin⁵²³⁴^ORCID,Kao Chien-Han¹²³⁴^ORCID,Chen Fang-Ming⁹¹⁰¹¹²³,Roffler Steve R.¹²³⁴¹²,Cheng Tian-Lu¹²³⁴⁵^ORCID

Affiliation:

1. Graduate Institute of Medicine

2. Kaohsiung Medical University

3. Kaohsiung

4. Taiwan

5. Drug Development and Value Creation Research Center

6. Department of Biological Science and Technology

7. National Chiao Tung University

8. Hsinchu

9. Department of Surgery

10. Faculty of Medicine

11. College of Medicine

12. Institute of Biomedical Sciences

Abstract

One-step formulation of BsAb with PLD is a simple method to enhance tumor specificity, internalization and the anti-cancer activity.

Funder

Ministry of Science and Technology, Taiwan

National Health Research Institutes

Academia Sinica

Kaohsiung Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/BM/C9BM00323A

Reference59 articles.

1. In vivo Biodistribution and Urinary Excretion of Mesoporous Silica Nanoparticles: Effects of Particle Size and PEGylation

2. Hapten-derivatized nanoparticle targeting and imaging of gene expression by multimodality imaging systems

3. Nanoparticle-Based Medicines: A Review of FDA-Approved Materials and Clinical Trials to Date

4. Sterically stabilized liposomes

5. Nanoparticles in the clinic

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