Anticancer potential of β-sitosterol and oleanolic acid as through inhibition of human estrogenic 17beta-hydroxysteroid dehydrogenase type-1 based on an <i>in silico</i> approach-Reference-Cited by-同舟云学术

Anticancer potential of β-sitosterol and oleanolic acid as through inhibition of human estrogenic 17beta-hydroxysteroid dehydrogenase type-1 based on an in silico approach

Published:2022 Issue:31 Volume:12 Page:20319-20329
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kristanti Alfinda Novi¹²^ORCID,Aminah Nanik Siti¹²^ORCID,Siswanto Imam¹³,Manuhara Yosephine Sri Wulan²⁴,Abdjan Muhammad Ikhlas¹⁵,Wardana Andika Pramudya¹⁵,Aung Ei Ei¹⁶,Takaya Yoshiaki⁷

Affiliation:

1. Departement of Chemistry, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia

2. Biotechnology of Tropical Medicinal Plants Research Group, Universitas Airlangga, Indonesia

3. Bioinformatic Laboratory, UCoE Research Center for Bio-Molecule Engineering, Universitas Airlangga, Surabaya, Indonesia

4. Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Surabaya 60115, Indonesia

5. PhD Student of Mathematics and Natural Sciences, Faculty of Science and Technology, Universitas Airlangga, Komplek Kampus C UNAIR, Jl. Mulyorejo, Surabaya, 60115, Indonesia

6. Departement of Chemistry, Yadanarbon University, Amarapura Township, Mandalay, Myanmar

7. Faculty of Pharmacy, Meijo University, 150 Yagotoyama, Tempaku, Nagoya, 468-8503 Japan

Abstract

We presented pharmacokinetic study, molecular docking, and MD simulation to study β-sitosterol and oleanolic acid compounds and potential HSD17B1 inhibitors.

Funder

Universitas Airlangga

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA03092F

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