Amorphous nanoparticles by self-assembly: processing for controlled release of hydrophobic molecules

Author:

Feng Jie12345ORCID,Zhang Yingyue453,McManus Simon A.453,Qian Rolane673,Ristroph Kurt D.453,Ramachandruni Hanu8910,Gong Kai1153125,White Claire E.1153125,Rawal Aditya131415ORCID,Prud'homme Robert K.453

Affiliation:

1. Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign

2. Urbana

3. USA

4. Department of Chemical and Biological Engineering, Princeton University

5. Princeton

6. Department of Chemical and Biomolecular Engineering, University of Maryland

7. College Park

8. Medicines for Malaria Venture

9. 1215 Meyrin

10. Switzerland

11. Department of Civil and Environmental Engineering, Princeton University

12. Andlinger Center for Energy and the Environment, Princeton University

13. Nuclear Magnetic Resonance Facility, Mark Wainwright Analytical Centre, University of New South Wales

14. Sydney

15. Australia

Abstract

We couple Flash NanoPrecipitation and spray drying as a scalable and versatile platform to formulate and recover amorphous nanoparticles for controlled release of hydrophobic drugs.

Funder

Bill and Melinda Gates Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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