Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity-Reference-Cited by-同舟云学术

Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity

Published:2014 Issue:24 Volume:43 Page:9045-9051
ISSN:1477-9226
Container-title:Dalton Trans.
language:en
Short-container-title:Dalton Trans.

Author:

Gobec Martina¹²³,Kljun Jakob⁴³⁵²³,Sosič Izidor¹²³,Mlinarič-Raščan Irena¹²³,Uršič Matija⁵²³,Gobec Stanislav¹²³,Turel Iztok⁴³⁵²³

Affiliation:

1. Faculty of Pharmacy

2. University of Ljubljana

3. SI-1000 Ljubljana, Slovenia

4. EN-FIST Centre of Excellence

5. Faculty of Chemistry and Chemical Technology

Abstract

The organoruthenium clioquinol complex induces copper-independent cell death in leukaemia cells by proteasome-independent inhibition of the NFκB signalling pathway.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/DT/C4DT00463A

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