Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity
Author:
Affiliation:
1. Faculty of Pharmacy
2. University of Ljubljana
3. SI-1000 Ljubljana, Slovenia
4. EN-FIST Centre of Excellence
5. Faculty of Chemistry and Chemical Technology
Abstract
The organoruthenium clioquinol complex induces copper-independent cell death in leukaemia cells by proteasome-independent inhibition of the NFκB signalling pathway.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/DT/C4DT00463A
Reference42 articles.
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5. Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs
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