Ru-Catalyzed highly diastereoselective hydrogenation of N-tert-butylsulfinyl ketimines for the synthesis of aryl glycine derivatives

Author:

Wei Qiaoling12345,Zhang Feng6785,Zhao Xiaofang12345,Wang Chao12345ORCID,Xiao Jianliang12345ORCID,Tang Weijun12345ORCID

Affiliation:

1. Key Laboratory of Applied Surface and Colloid Chemistry of Ministry of Education

2. and School of Chemistry & Chemical Engineering

3. Shaanxi Normal University

4. Xi'an

5. China

6. College of Science

7. Hunan Agricultural University

8. Changsha

Abstract

A Ru-Pincer catalyst enables the diastereoselective hydrogenation of N-tert-butylsulfinyl ketimino esters, affording a promising method for the synthesis of aryl glycine derivatives.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference75 articles.

1. G. C. Barrett , Chemistry and Biochemistry of the Amino Acids, Chapman and Hall, London, 1985

2. R. M. Williams , Synthesis of Optically Active Amino Acids, Pergamon Press, Oxford, 1989

3. A. B. Hughes , Amino Acids, Peptides and Proteins in Organic Chemistry, Wiley-VCH, Weinheim, 2009

4. Recent Developments in the Catalytic Asymmetric Synthesis of α- and β-Amino Acids

5. Asymmetric synthesis of arylglycines

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