Inhibitory effect of cytotoxic nitrogen-containing heterocyclic stilbene analogues on VEGF protein secretion and VEGF, hTERT and c-Myc gene expression-Reference-Cited by-同舟云学术

Inhibitory effect of cytotoxic nitrogen-containing heterocyclic stilbene analogues on VEGF protein secretion and VEGF, hTERT and c-Myc gene expression

Published:2015 Issue:10 Volume:6 Page:1809-1815
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Martí-Centelles Rosa¹²³⁴,Murga Juan¹²³⁴,Falomir Eva¹²³⁴,Carda Miguel¹²³⁴,Alberto Marco J.⁵⁶⁷⁴

Affiliation:

1. Depart. de Química Inorgánica y Orgánica

2. Univ. Jaume I

3. E-12071 Castellón

4. Spain

5. Depart. de Química Orgánica

6. Univ. Valencia

7. E-46100 Burjassot

Abstract

Twenty-one nitrogen-containing heterocyclic stilbenes were synthesized. Their cytotoxicity and effect on VEGF protein secretion as well asVEGF,hTERTandc-Mycgene expression were evaluated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00197H

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