Naphthalimide-based fluorescent probe for selectively and specifically detecting glutathione in the lysosomes of living cells-Reference-Cited by-同舟云学术

Naphthalimide-based fluorescent probe for selectively and specifically detecting glutathione in the lysosomes of living cells

Published:2016 Issue:4 Volume:52 Page:721-724
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Cao Meijiao¹²³⁴⁵,Chen Haiyan⁶⁷⁸⁹¹⁰,Chen Dan⁶⁷⁸⁹¹⁰,Xu Zhiqiang¹²³⁴⁵,Liu Sheng Hua¹²³⁴⁵,Chen Xiaoqiang¹¹¹²¹³⁹¹⁰,Yin Jun¹²³⁴⁵

Affiliation:

1. Key Laboratory of Pesticide and Chemical Biology

2. Ministry of Education

3. College of Chemistry

4. Central China Normal University

5. Wuhan 430079

6. Department of Biomedical Engineering

7. School of Engineering

8. China Pharmaceutical University

9. Nanjing 210009

10. P. R. China

11. State Key Laboratory of Materials-Oriented Chemical Engineering

12. College of Chemistry and Chemical Engineering

13. Nanjing Tech University

Abstract

A novel naphthalimide-based fluorescent probe employing a sulfonamide unit as a thiol-responsive group is reported. It is capable of efficiently distinguishing GSH from cysteine and homocysteine and can visualize the level of GSH in lysosomes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CC/C5CC08328A

Reference47 articles.

1. Structure, mechanism and regulation of peroxiredoxins

2. The importance of glutathione in human disease

3. Chemistry of Molecular Imaging

4. Fluorescent probes for sensing and imaging

5. Imaging beyond the proteome

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