Cytotoxicity assessment of exfoliated MoS2 using primary human mast cells and the progenitor cell-derived mast cell line LAD2

Author:

Lin Hazel1,del Rio Castillo Antonio Esau2,González Viviana Jehová3ORCID,Bonaccorso Francesco2,Vázquez Ester3ORCID,Fadeel Bengt4ORCID,Bianco Alberto1ORCID

Affiliation:

1. CNRS, Immunology, Immunopathology and Therapeutic Chemistry, UPR 3572, University of Strasbourg, ISIS, 67000 Strasbourg, France

2. BeDimensional, Lungo Torrente Secca 30r, Genoa, Italy

3. Biograph Solutions, Regional Institute of Applied Scientific Research (IRICA), Department of Organic Chemistry, Faculty of Science and Chemistry Technologies, University of Castilla-La Mancha, Ciudad Real 13071, Spain

4. Nanosafety & Nanomedicine Laboratory, Institute of Environmental Medicine, Karolinska Institutet, 177 77 Stockholm, Sweden

Abstract

Assessment of the impact of molybdenum disulfide on immune cells (e.g., mast cells) is required to ascertain its biocompatibility in view of its future development for biomedical applications.

Funder

Agence Nationale de la Recherche

European Commission

Centre National de la Recherche Scientifique

Centre International de Recherche aux Frontières de la Chimie

Publisher

Royal Society of Chemistry (RSC)

Reference67 articles.

1. [IMA] International Molybdenum Association , Molybdenum Uses , accessed 7 Apr 2020 , https://www.imoa.info/molybdenum-uses/molybdenum-chemistry-uses/molybdenum-chemistry-uses.php

2. [ATSDR] US Agency for Toxic Substances and Disease Registry , Toxicological Profile for Molybdenum , Apr 2017 Version, accessed 7 Apr 2020 , https://www.atsdr.cdc.gov/ToxProfiles/tp212.pdf

3. Metal hypersensitivity and pro-inflammatory cytokine production in patients with failed orthopedic implants: A case-control study

4. Corrosion of Metallic Biomaterials: A Review

5. Cobalt-Chromium-Molybdenum Alloy Causes Metal Accumulation and Metallothionein Up-Regulation in Rat Liver and Kidney

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