Vicinal abasic site impaired processing of a Tg:G mismatch and 8-oxoguanine lesions in three-component bistranded clustered DNA damage-Reference-Cited by-同舟云学术

Vicinal abasic site impaired processing of a Tg:G mismatch and 8-oxoguanine lesions in three-component bistranded clustered DNA damage

Published:2018 Issue:32 Volume:8 Page:17921-17926
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kumari Bhavini¹²³⁴,Jha Pravin⁵⁶⁴,Sinha Kislay K.⁵⁶⁴,Das Prolay¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. IIT Patna

3. Patna-801103

4. India

5. Department of Biotechnology

6. NIPER Hajipur

Abstract

The occurrence of 7,8-dihydro-8-oxo-2′deoxyguanosine (8-oxodG), thymine glycol:guanine (Tg:G) mismatch and abasic site DNA damage lesions in close proximity induce repair refractive non-DSB cluster.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA01992D

Reference36 articles.

1. Oxidative DNA damage: mechanisms, mutation, and disease

2. Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sites

3. Oxidative damage to 5-methylcytosine in DNA

4. Abasic sites in DNA: repair and biological consequences in Saccharomyces cerevisiae

5. 8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways

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