Determination of composition distributions of multi-particle crystalline samples by sequential dissolution with concomitant particle sizing and solution analysis
Author:
Affiliation:
1. School of Chemistry
2. Analytical and Biological Chemistry Research Facility
3. Synthesis and Solid-state Pharmaceutical Centre
4. University College Cork
5. Republic of Ireland
Abstract
Sequential dissolution of multi-particle samples with before-and-after sizing gave composition data that can be assigned to defined sample particle regions.
Funder
Science Foundation Ireland
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Materials Science,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CE/C8CE00206A
Reference47 articles.
1. Effect of solid-solution softening of crystalline materials: Review
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5. Approaches to Assessment, Testing Decisions, and Analytical Determination of Genotoxic Impurities in Drug Substances
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