Microfluidic device for single step measurement of protein C in plasma samples for sepsis prognosis-Reference-Cited by-同舟云学术

Microfluidic device for single step measurement of protein C in plasma samples for sepsis prognosis

Published:2022 Issue:13 Volume:22 Page:2566-2577
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Damodara Sreekant¹,Arora Jaskirat²,Dwivedi Dhruva J.²,Liaw Patricia C.²,Fox-Robichaud Alison E.²,Selvaganapathy P. Ravi¹^ORCID,Canadian Critical Care Translational Biology Group

Affiliation:

1. Department of Mechanical Engineering, McMaster University, Hamilton, Canada

2. Department of Medicine, McMaster University, Hamilton, Canada

Abstract

We report a microfluidic device that combines isoelectric gates with miniaturized metal affinity chromatography for the measurement of protein C in plasma.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Canada Research Chairs

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D1LC01084K

Reference38 articles.

1. The Role of Activated Protein C in Sepsis

2. Clinical evaluation of protein C: A comparative review of antigenic and functional assays

3. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

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