Fluorescent probes for formaldehyde based on formaldehyde-promoted C–N cleavage of azanyl carbamates

Author:

Xing Wanjin1,Li Yang1,Que Yulin1,Xu Huan2,Wang Wei3,Lou Kaiyan1ORCID

Affiliation:

1. State Key Laboratory of Bioreactor Engineering, Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Shanghai Key Laboratory of New Drug Design, and Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science & Technology, 130 Meilong Road, Shanghai 200237, China

2. School of Public Health, Anhui University of Science and Technology, Hefei, Anhui Province, 231131, China

3. Department of Pharmacology and Toxicology and BIO5 Institute, University of Arizona, Tucson, AZ 85721-0207, USA

Abstract

C–N cleavage of 3-nitrophenylazanyl N-arylcarbamate promoted by formaldehyde-induced intramolecularity was utilized for formaldehyde detection in the NAP-FAP2 series of fluorescent probes.

Funder

Natural Science Foundation of Shanghai

Shanghai Municipal Education Commission

National Natural Science Foundation of China

East China University of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

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