Metallomic study on the metabolism of RAPTA-C and cisplatin in cell culture medium and its impact on cell accumulation-Reference-Cited by-同舟云学术

Metallomic study on the metabolism of RAPTA-C and cisplatin in cell culture medium and its impact on cell accumulation

Published:2018 Issue:3 Volume:10 Page:455-462
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Holtkamp Hannah U.¹²³⁴,Movassaghi Sanam¹²³⁴,Morrow Stuart J.¹²³⁴,Kubanik Mario¹²³⁴,Hartinger Christian G.¹²³⁴^ORCID

Affiliation:

1. School of Chemical Sciences

2. University of Auckland

3. Auckland 1142

4. New Zealand

Abstract

The different extracellular speciation of cisplatin and the organoruthenium developmental anticancer agent RAPTA-C impacts the accumulation in cancer cells.

Funder

University of Auckland

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MT/C8MT00024G

Reference80 articles.

1. Interactions of Antitumor Metallodrugs with Serum Proteins: Advances in Characterization Using Modern Analytical Methodology

2. In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

3. Cellular uptake and subcellular distribution of ruthenium-based metallodrugs under clinical investigation versus cisplatin

4. The development of RAPTA compounds for the treatment of tumors

5. Ligand substitutions between ruthenium–cymene compounds can control protein versus DNA targeting and anticancer activity

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