Large-sized graphene oxide synergistically enhances parenchymal hepatocyte IL-6 expression monitored by dynamic imaging

Author:

Zhang Yulong123,Ma Cong4563,Wang Zhengjun123,Zhou Qianqian123,Sun Sujing123,Ma Ping123,Lv Liping123,Jiang Xinquan4563,Wang Xiaohui12378,Zhan Linsheng123ORCID

Affiliation:

1. Institute of Health Service and Transfusion Medicine

2. Beijing 100850

3. P. R. China

4. School of Public Health

5. Shandong First Medical University & Shandong Academy of Medical Sciences

6. Tai'an

7. Key Laboratory of Advance Energy Materials Chemistry (Ministry of Education)

8. College of Chemistry

Abstract

Graphene Oxide synergized with pro-inflammation cytokines secreted by M1 polarized Kupffer cells and initiated hepatocyte IL-6 expression through individual NF-κB signal pathway.

Funder

Mega-projects of Science Research for the 10th Five-Year Plan

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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