Microengineered peripheral nerve-on-a-chip for preclinical physiological testing-Reference-Cited by-同舟云学术

Microengineered peripheral nerve-on-a-chip for preclinical physiological testing

Published:2015 Issue:10 Volume:15 Page:2221-2232
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Huval Renee M.¹²³,Miller Oliver H.⁴²³,Curley J. Lowry¹²³,Fan Yuwei¹²³,Hall Benjamin J.⁴²³⁵²,Moore Michael J.¹²³⁴²

Affiliation:

1. Tulane University - Biomedical Engineering

2. New Orleans

3. USA

4. Tulane University - Neuroscience Program

5. Tulane University - Cell & Molecular Biology

Abstract

A microscale, organotypicin vitromodel of sensory peripheral nerve tissue may be assessed with clinically-relevant morphological and physiological measures for use as a drug screening assay for selecting promising lead compounds with higher chances of late-stage success.

Funder

Medical Research and Materiel Command, U.S. Army Medical Department

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2015/LC/C4LC01513D

Reference42 articles.

1. Microengineered physiological biomimicry: Organs-on-Chips

2. Biomimetic tissues on a chip for drug discovery