Csp<sup>3</sup>–H monofluoroalkenylation <i>via</i> stereoselective C–F bond cleavage-Reference-Cited by-同舟云学术

Csp³–H monofluoroalkenylation via stereoselective C–F bond cleavage

Published:2022 Issue:16 Volume:58 Page:2734-2737
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Hu Ying¹,Liu Xingchen¹,Ren Zhouyang¹,Hu Binjing¹,Li Jie¹^ORCID

Affiliation:

1. Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Ren-Ai Road 199, 215123 Suzhou, China

Abstract

A practical nickel- and photoredox-catalyzed Csp3–H monofluoroalkenylation with gem-difluoroalkenes for the synthesis of stereodefined tetrasubstituted fluoroalkenes with complete control of stereoselectivity has been developed.

Funder

Soochow University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D1CC06247F

Reference45 articles.

1. Late-Stage Fluorination: Fancy Novelty or Useful Tool?

2. Introduction of Fluorine and Fluorine-Containing Functional Groups

3. Promising reagents for difluoroalkylation

4. Recent Progress toward the Introduction of Functionalized Difluoromethylated Building Blocks onto C(sp2) and C(sp) Centers

5. J. P.Begue and D.Bonnet-Delpon , Bioorganic and Medicinal Chemistry of Fluorine , Wiley : Hoboken, NJ , 2008

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Two-in-One Role of Benzophenone in Photoinduced C(sp³)–H Monofluoralkenylation: Hydrogen-Atom Transfer and Single-Electron Transfer;The Journal of Organic Chemistry;2024-05-22

2. Synthesis of Fluorinated Compounds by Nickel-Catalyzed Defluorinative Cross-Coupling Reactions;ACS Catalysis;2023-09-01

3. C−H Bond Activation Relay (CHAR) of Proline Ester Derivatives Promoted by In Situ Triarylamine Radical Cation: Selective Synthesis of 4‐Bromopyrrole Derivatives;Chemistry – A European Journal;2023-03-14

4. Visible-Light-Induced Monofluoroalkenylation and gem-Difluoroallylation of Inactivated C(sp³)–H Bonds via 1,5-Hydrogen Atom Transfer (HAT);The Journal of Organic Chemistry;2023-03-07

5. Recent Advances in Alkenyl sp² C–H and C–F Bond Functionalizations: Scope, Mechanism, and Applications;Chemical Reviews;2022-10-14