Construction of quaternary carbon centers by KOtBu-catalyzed α-homoallylic alkylation of lactams with 1,3-dienes

Author:

Wang Shang1,Xiang Yunfei1,Chen Tiantian1,Wu Xiang1,Xing Dong1ORCID

Affiliation:

1. Shanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China

Abstract

We report a KOtBu-catalyzed α-homoallylic alkylation of lactams with 1,3-dienes.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference61 articles.

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5. Catalytic addition of C–H bonds across C–C unsaturated systems promoted by iridium(i) and its group IX congeners

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