A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor-Reference-Cited by-同舟云学术

A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor

Published:2020 Issue:1 Volume:1 Page:13-25
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Raimi Olawale G.¹^ORCID,Hurtado-Guerrero Ramon¹^ORCID,Borodkin Vladimir¹^ORCID,Ferenbach Andrew¹^ORCID,Urbaniak Michael D.²^ORCID,Ferguson Michael A. J.²,van Aalten Daan M. F.¹^ORCID

Affiliation:

1. Division of Gene Regulation and Expression, School of Life Sciences, University of Dundee, Dow Street, DD1 5EH Dundee, UK

2. Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dow Street, DD1 5EH Dundee, UK

Abstract

UDP-N-acetylglucosamine pyrophosphorylase (UAP1) catalyses the last step in eukaryotic biosynthesis of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), converting UTP and GlcNAc-1P to the sugar nucleotide.

Funder

Medical Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CB/C9CB00017H

Reference31 articles.

1. The cell wall stress response in Aspergillus niger involves increased expression of the glutamine : fructose-6-phosphate amidotransferase-encoding gene (gfaA) and increased deposition of chitin in the cell wall

2. Review: Cell wall assembly in yeast

3. Dynamics of cell wall structure inSaccharomyces cerevisiae

4. Aspergillus fumigatuscell wall: composition and biosynthesis

5. Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the α-d-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes

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