Enzyme-catalysed enantioselective oxidation of alcohols by air exploiting fast electrochemical nicotinamide cycling in electrode nanopores

Author:

Wan Lei1234ORCID,Heath Rachel S.56784,Siritanaratkul Bhavin1234ORCID,Megarity Clare F.1234ORCID,Sills Adam J.1234,Thompson Matthew P.56784,Turner Nicholas J.56784ORCID,Armstrong Fraser A.1234ORCID

Affiliation:

1. Department of Chemistry

2. University of Oxford

3. Oxford

4. UK

5. School of Chemistry

6. University of Manchester

7. Manchester Institute of Biotechnology

8. Manchester M1 7DN

Abstract

Enantioselective conversion of alcohols to ketones using air as the oxidant is achieved with high rates and efficiency using an indium tin oxide electrode in which an alcohol dehydrogenase and a NADPH recycling enzyme are confined within nanopores.

Funder

Biotechnology and Biological Sciences Research Council

SCG Chemicals

European Research Council

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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