Comparison of morphological and functional restoration between asymmetric bilayer chitosan and bladder acellular matrix graft for bladder augmentation in a rat model

Author:

Xiao Dongdong12345ORCID,Wang Qiong678910,Yan Hao12345,Qin An11121334,Lv Xiangguo12345,Zhao Yang12345,Zhang Ming12345,Zhou Zhe12345,Xu Jiping6133414,Hu Qiaoling1516171810,Lu Mujun12345ORCID

Affiliation:

1. Department of Urology and Andrology

2. Ren Ji Hospital

3. School of Medicine

4. Shanghai Jiao Tong University

5. Shanghai 200001

6. Department of Urology

7. The Sun Yat-sen Memorial Hospital

8. Sun Yat-sen University

9. Guangzhou 510120

10. China

11. Department of Orthopedics

12. Shanghai Key Laboratory of Orthopedic Implants

13. Shanghai Ninth People's Hospital

14. Shanghai 200011

15. MOE Key Laboratory of Macromolecular Synthesis and Functionalization

16. Department of Polymer Science and Engineering

17. Zhejiang University

18. Hangzhou 310027

Abstract

Asymmetric bilayer chitosan promoted bladder reconstruction with enhanced smooth muscle regeneration and angiogenesis, and functional restoration with augmented bladder capacity.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference53 articles.

1. M. C. Adams and D. B.Joseph, in Walsh-Campbell Urology, ed. A. J. Wein, L. R. Kavoussi, A. C. Novick, A. W. Partin and C. A. Peters, Saunders Elsevier, Philadelphia, 2007

2. R. D. Cespedes and E. J.McGuire, in Glenn's Urology, ed. J. F. Glenn, S. D. Graham and T. E. Keane, Lippincott Williams and Wilkins, Philadelphia, 2004

3. D. M. Dahl and W. S.McDougal, in Campbell-Walsh Urology, ed. A. J. Wein, L. R. Kavoussi, A. C. Novick, A. W. Partin and C. A. Peters, Saunders Elsevier, Philadelphia, 2007

4. Augmentation Cystoplasty Rates at Children’s Hospitals in the United States: A Pediatric Health Information System Database Study

5. Bladder augmentation: Complications in the pediatric population

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